AG James and AG Tong lead bipartisan coalition of 42 AGs in urging congress to pass legislation to protect communities from illicit Xylazine

Published Date: Mar 30, 2026

AG ​Mayes today joined a bipartisan coalition of 40 other attorneys general in calling on Congress to pass the Combating Illicit Xylazine Act. The bipartisan legislation would classify the dangerous animal tranquilizer xylazine – which is often mixed with fentanyl and other opioids – as a federal controlled substance to better protect communities and reduce opioid overdose deaths. In a letter to House and Senate leadership, Attorney General Mayes and the coalition explain the dangers of illicit xylazine, which is causing an increasing number of opioid overdose deaths, and argue that federally classifying xylazine as a controlled substance is essential to helping law enforcement stop the spread of the drug.

“Xylazine is making already dangerous street drugs even more harmful. I urge Congress to take action to protect Arizona communities from this substance.” – AG Mayes

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